Log In|Sign Up
EN
A bicistronic reporter cassette containing a loxP-flanked neomycin cassette, an encephalomyocarditis virus (EMCV) IRES element, and enhanced yellow fluorescent protein (EYFP) was introduced immediately after the Ifnb1 STOP codon. The use of 129 background embryonic stem (ES) cells expressing cre under the control of the germline-specific protamine (Prm) promoter allowed for the cre-mediated excision of the floxed neomycin gene from the male germline. The line was backcrossed to C57BL/6 to breed cre out of the line. (J:152138)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
