A 3970-bp segment located from 16.3-20.3 kb downstream of Mef2c exon 1 and 51.1-55.1 kb upstream of the first coding exon (exon 5) was used to direct human placental alkaline phosphatase expression. This region of the mouse Mef2c gene contains enhancer and promoter sequences sufficient to direct expression in mouse embryos to the anterior heart field and its derivatives in the pharyngeal mesoderm, the right ventricle, and the outflow tract. (details provided by Dr. Brian L Black, personal Communication) (J:98489, J:152141)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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