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This allele was created by transfer of a male natural killer T cells nucleus (C57BL/6 x 129/Sv)F1 background) into an enucleated oocyte. A blastocyte was grown and transferred into psuedopregnant mouse. One of the Tcra alleles in the transferred nuclei had a productive, in-frame recombination of the Valpha14-Jalpha281 gene segments and it was this allele that was propagated. Sequence analysis determined this productive recombination occurred on the genetic locus contributed by the 129/Sv parent. (J:152069)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
