An in-frame termination codon was inserted just after the A and B common region in the constant region third exon along with a floxed neomycin resistance gene cassette. The neo cassette was removed by germ line cre-mediated recombination. Mice do not produce the B-type transcript but instead only a truncated transcript that lacks A-type cytoplasmic tail. (J:151979)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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