An in-frame termination codon was inserted just after the A and B common region in the constant region third exon along with a floxed neomycin resistance gene cassette. The neo cassette was removed by germ line cre-mediated recombination. Mice do not produce the B-type transcript but instead only a truncated transcript that lacks A-type cytoplasmic tail. (J:151979)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count