Log In|Sign Up
EN
An IRES-cre fragment with a nuclear localization signal sequence (nls) and an SV40 polyA sequence was inserted into a plasmid containing genomic fragments of Ppp1rb1 from 3 clones. The transgenic construct was injected into fertilized C57BL/6 oocytes. Two potential founders were obtained but only one founder was successfully bred to generate the line. Insertion of a single copy of the transgene was verified by Southern blot. (J:127863)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
