Exons 6 and 7 were replaced with a floxed neo, floxed STOP, and human RUNX1 coding region. When the floxed neo and STOP cassette are removed by cre-mediated recombination, a fusion product of mouse Etv6 and human RUNX1 (or TEL-AML1) was created. (J:151639)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count