Founder mice derived from BALB/c ES cells carrying the Ifnb1tm1.2Lien mutation were crossed with K14-cre transgenic mice to remove the coding exon from the germline and bring the reporter construct under the control of the endogenous promoter. Reporter expression was detected in numerous tissues after viral infection. (J:151854)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
BALB/cJ
Targeted
Intragenic deletion
--
1
--
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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