A codon-improved cre (icre) containing a nuclear localization signal (nls) and an SV40 polyadenylation signal was fused to the initiation codon of the Nkx6-2 gene in a bacterial artificial chromosome (BAC). The construct was injected into fertilized oocytes. (J:125700)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count