An EGFP cassette was inserted in-frame at the translational start site in exon 1. A floxed neomycin cassette was also inserted downstream of exon 2. The fusion protein was detected in single-positive thymocytes. Because homozygote mice are viable and have normal lymphocyte numbers, the fusion protein was assumed to retain the function of the endogenous protein. (J:151604)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
1
--
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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