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Sequence encoding three copies of the hemagglutinin (HA) epitope YPYDVPDYA were fused in frame 3' to the single exon of the gene locus. A floxed neomycin cassette was inserted downstream of the exon and was later removed by breeding founders with a cre deleter strain. Mice homozygous for this C-terminal "tagged" allele recapitulated wild-type expression patterns of the endogenous protein. Protein function was unaltered as determined by phenotypic analysis. (J:151244)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
