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The first polyalanine tract found in exon 2 was expanded by the insertion 8 GCT alanine tracts bringing the total number of alanine codons in tract 1 to 23. In addition loxP sites were inserted around exon 2 and an frt flanked neo cassette was inserted in intron 2 via homologous recombination. Flp mediated recombination then removed the neo cassette. (J:151082)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
