A loxP site was inserted upstream of exon 13 and a floxed neomycin cassette was inserted after the untranslated region encoded in exon 14. Correct targeting was confirmed by genomic PCR. (J:150982)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count