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EN
A cassette containing 25 tandem I-SceI target sites (S. cerevisiae) endonuclease recognition site (TAGGGATAACAGGGTAAT) was inserted into intron 1 of the gene. A floxed neomycin cassette was included upstream of the I-SceI cassette and was subsequently removed by transient expression of cre recombinase. Correct targeting was confirmed by Southern blotting. (J:150339)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
