A 4.3 kb fragment of the Smad7 promoter was cloned into an expression vector in front of the EGFPcre sequence. The linearized construct was injected into C3H/FeJ zygotes. Two lines were generated that gave similar expression patterns when crossed to the R26R reporter line, and only one line was studied further. (J:150864)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count