A gene trap vector containing a splice-acceptor sequence upstream of the reporter gene, beta-geo (a fusion gene of beta-galactosidase and neomycin phosphotransferase II) inserted into intron 1. Immunoblot analysis showed a complete loss of the encoded protein in the lysates from whole embryos and immortalized MEFs. (J:226309)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count