Trapped gene association determined by genome coordinate overlap and strand. Exon 7 of the gene locus was interrupted by insertion of the gene trapping vector pT1betageo. The vector fusion gene's chain termination signal results in loss of all downstream sequences. While the mutant allele was detected in spermatozoa from highly chimeric mice, no embryos carrying the mutant allele were detected. This allele may have a dominant negative effect.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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