Log In|Sign Up
EN
Insertion of a beta-gal and neo cassette within 6174 bases 3' of the beginning of intron 3 of Vrk1. The predicted product only contains the N-terminal 72 amino acids fused with beta-gal and is catalytically inert. However, RT-PCR demonstrated only a 4.5- to 6.4-fold decrease in full length message in various adult tissues, confirmed by immunoblots, indicating this is a hypomorphic allele. (J:156653)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
