A gene trap construct inserted after exon 1, introducing a polyadenylation site and a premature stop codon. RT-PCR and immunoblotting experiments confirmed the loss of wild-type transcript and protein, respectively. (J:234118)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count