Gene trap insertion was in intron 1 of Poll and also the promoter region of Dpcd near the transcriptional start site. These two genes overlap, and the gene trap inserted into this overlapping region. By RT-PCR analysis, no endogenous Poll transcript was detected in homozygous tissues. Similary, no endogenous Dpcd transcript was detected in homozygous tissues. (J:171184)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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