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The gene trap targeting vector (consisting of a splice acceptor sequence (SA) followed by a beta-geo selection cassette and a polyadenylation signal) integrated into the intron between exons 2 and 3. Northern blot of kidney and brain confirmed that homozygous mice lack detectable mRNA.
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
