A gene trap cassette inserted in to intron 1. The absence of transcribed mRNA was verified by quantitative RT-PCR analysis using RNA isolated from embryonic day 13.5 (E13.5) mouse embryonic fibroblasts. Immunoblotting confirmed the absence of encoded protein from lung and kidney lysates of homozygous mutant mice. (J:226661)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
4
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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