A gene trap vector inserted into intron 2. The endogenous full-length protein is replaced by a fusion-protein encoded by the first two Mena exons and the reporter gene. However, a low amount of endogenous full length 140 kDa isoform protein is found in brain. but not other tissues where the gene is normally expressed. (J:250072)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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