A gene trap insertion located in the third intron results in an in frame fusion transcript consisting of exons 1 (untranslated region), 2, and 3, a CD2-derived transmembrane domain, beta galactosidase and neomycin. LacZ expression is detected at E8.5 in a predominantly endodermal pattern and in multiple tissues at later stages. (J:155941)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
6
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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