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The gene trap vector insertion site was mapped to nucleotide 12535 within intron 1 of the Dcp2 gene. Western analysis of several organs from 4-week-old wild-type (WT) and homozygous littermates revealed the mice containing a homozygous insertion of the gene trap vector were not completely devoid of Dcp2 expression and were instead phenotypically hypomorphic with reduced protein expression in the different tissues that Dcp2 can normally be detected. (J:166846)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
