Insertion of this gene trap between exons 2 and 3 results in splicing from exon 2 to the beta-galactosidase/neomycin genes in the cassette. Northern blot of testis RNA and western blot of testis protein from homozygous mice demonstrated that no detectable normal transctipts nor protein product are expressed from this allele.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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