Trapped gene association determined by genome coordinate overlap and strand. This gene trap is inserted approximately 3819 nucleotides 3' to exon 37. The gene trap insertion interrupts a predicted armadillo fold and leads to a truncated protein, preserving 1,447 amino acids upstream of the insertion. The truncation will result in the loss of the USP_3 domain required for catalytic activity. No full-length protein is detectable but a beta-geo fusion protein is detected that is not catalytically active. (J:303991)
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参考文献
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
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1
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2

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标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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N: 正常表型
(#): 上标括号内为相关疾病数量
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