Trapped gene association determined by genome coordinate overlap and strand. This gene trap is inserted approximately 3819 nucleotides 3' to exon 37. The gene trap insertion interrupts a predicted armadillo fold and leads to a truncated protein, preserving 1,447 amino acids upstream of the insertion. The truncation will result in the loss of the USP_3 domain required for catalytic activity. No full-length protein is detectable but a beta-geo fusion protein is detected that is not catalytically active. (J:303991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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