The En2 intron-Geo vector (encoding a Gal-Neo fusion protein) is inserted at intron 1, 230 bp upstream of exon 2 of the gene. The construct insertion results an interruption the coding region after amino acid 28, upstream of the Ran binding domain in the encoded protein. (J:250929)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count