The En2 intron-Geo vector (encoding a Gal-Neo fusion protein) is inserted at intron 1, 230 bp upstream of exon 2 of the gene. The construct insertion results an interruption the coding region after amino acid 28, upstream of the Ran binding domain in the encoded protein. (J:250929)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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