The gene trap inserted into exon 1 (encoding 34 amino acids and lacking the ER-targeting TM segment), and fused the gene encoding beta-Galactosidase to the endogenous sequence. Analysis of protein expression in mouse spleen tissue extracted from homozygous mice confirmed the absence of the encoded protein expression by immunoblot analysis. (J:183788)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count