A rFlpROSA-geo cassette containing a splicing acceptor site and a polyadenylation sequence inserted between exons 3 and 4 of the gene. The insertion creates a null allele with no detectable transcript or protein expressed from this allele, and embryos carrying this allele turn blue upon incubation in X-gal.
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count