Trapped gene association determined by genome coordinate overlap and strand. Gene trap insertion is in intron 8 and resuls in disruption of the catalytic domain encoded be exons 2-12. Q-PCR demonstrated the absence of specific mRNA in homozygotes and Western blot analysis confirmed the absence of protein. (J:179810)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Gene trapped
Insertion of gene trap vector
--
1
4
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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