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A gene trap containing a beta-geo reporter inserted into the sequences after exon 9, resulting in a truncated protein in which 10 of the 11 zinc fingers are lost. Real time PCR analysis revealed no detectable mRNA in the heart of E12.5 homozygous mutant embryos. Western blot analysis confirmed the absence of protein expression of both the full-length (Casz1a) and shorter (Casz1b) isoform in E14.5 whole heart lysates. (J:242127)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
