The insertion site of the gene-trap vector is between exons 21 and 22 of the gene. A truncated transcript is expressed from this allele, as shown by in situ hybridization with a cRNA probe that maps to the 5 end of the transcript, but not full-length transcript. A fusion protein consisting of amino acids 1870 (of 1524) of the endogenous protein fused to the beta-geo reporter is expressed from this allele, in a pattern similar to endogenous expression. (J:255065)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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