A gene trap vector, pGT01xf, containing the beta-geo reporter gene (beta-galactosidase and neomycin resistance fusion gene) was inserted into intron 1 of the Ash1l gene. Immunohistochemical analysis of uterus tissue from 3 and 4 week old homozygous females and epididymis from homozygous males also shows diminished Ash1l protein. (J:222720)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count