Most of the open reading frame was replaced with a cassette containing EGFP, cre, and frt flanked neo that was inserted out of frame with the initiation site. The inserted cassette replaced amino acids 20 through 315 of the total 321 amino acids of the endogenous protein. Germ line, flp mediated recombination removes the neo cassette. (J:150802)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion, Intragenic deletion
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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