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Exon 1 through part of intron 2 was replaced with the corresponding sequence from C57BL/6 mice. Although the ES cells used to create this allele were (129S1/SvImJ x NOD/ShiLtJ)F1 the targeting event was mapped to the NOD allele. The floxed neo cassette downstream of the inserted sequence was removed by transient cre expression in ES cells. (J:150823)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
