Log In|Sign Up
EN
Dominant negative JNK1 (Mapk8) and JNK2 (Mapk9) cDNAs in which the dual phosphorylation motif TPY was changed to APF were each fused to a 5.5 kb cardiac specific alpha myosin heavy chain promoter. The constructs were mixed and coinjected into FVB/N oocytes. Three independent lines including 22.4 which was chosen as a representative, and 6.1 were found to coexpress equal amounts of each dominant negative protein. (J:85947)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
