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The rabbit PRKCA cDNA carrying the dominant negative L368A mutation was fused to the cardiac-specific alpha myosin heavy chain (Myh6) mouse promoter. The promoter is minimally active/attenuated through the ablation of three GATA sites and two thyroid-like response elements. Seven copies of tetracycline-responsive promoter element (tetO) are fused to the promoter. (J:88510, J:132098)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
