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The targeting vector was designed to replace exons 9-14 and part of exon 15, which encode the entire predicted catalytic domain, with a floxed neomycin cassette. Founder mice were crossed with cre transgenic mice to remove the neomycin cassette. No protein product was detected in homozygote olfactory epithelium as determined by immunohistochemistry. (J:150514)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
