A loxP site and an frt flanked pGKNeo cassette were inserted upstream of exon 13. A modified YFP reporter (Venus) was inserted in frame in exon 15. Mice expressing the fusion protein encoded by this modification were crossed with an unspecified FLP expressing mouse line to excise the neomycin selection cassette. The resulting allele has exons 13 through the coding portion of exon 15 flanked by loxP sites. (J:132370)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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