Two transgenic constructs were co-injected into fertilized oocytes. The first construct (GFAP-fLuc) included the firefly luciferase gene under the control of the 2.2kb human GFAP, glial fibrillary acidic protein promoter. The other construct (GAPDH-RLuc) consisted of the Renilla luciferase gene under the control of the 0.5kb human GAPDH, glyceraldehyde-3-phosphate dehydrogenase promoter. Founder line 172.9 was subsequently established. (J:150335)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(FVB x C57BL/6)F1
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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