The lacZ reporter was placed under the control of the Cdkn1a promoter. Seven of twelve founders passed the transgene on to the next generation. Three lines showed sufficiently high levels of lacZ expression for further study. Line 44 displays no basal lacZ expression but does show high levels of expression after etoposide treatment. (J:150334)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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