A loxP site was inserted upstream of exon 4 and a loxP site and frt flanked neo cassette were inserted downstream of exon 4 via homologous recombination. (J:150213)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count