Germ line, flp mediated recombination removed the neo cassette leaving exon 5 floxed and the modified exon 5 not expressed. Cre mediated recombination to remove the wild-type exon 5 is needed to allow for expression of the modified exon 5. (J:150043)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion, Nucleotide substitutions
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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