Tnfsf14 coding sequence was driven by the proximal Lck promoter and human CD2 enhancer with human growth hormone gene (polyadenylation site) included downstream. Lines 24 and 27 in a C57BL/6 background were selected for further investigation with similar phenotypes observed in both lines. Expression in lymphocytes was confirmed by flow cytometry analysis of lymphocytes. (J:129951)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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