The gene trap vector pGT1Lxf was inserted into the first intron. Quantitative real time RT-PCR analysis detected very low levels of expression in all organs examined except the brain. Expression in the brain is not significantly different from littermate controls. Phosphatase activities are reduced in all tissue homogenates except the brain suggesting this is a hypomorphic allele. (J:149782)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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