A loxP site was inserted 5' of the promoter and a floxed neo cassette was inserted 3' of coding exon. Cre mediated recombination removed the floxed neo leaving the coding region floxed. (J:84909)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count