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A floxed neomycin cassette replaced 4 kb of genomic sequence that included the V5 gene segment and the intervening sequence that lies between the V5 gene segment and the TEA promoter. Cre-mediated deletion of the neomycin cassette removed the V5 gene segment and brought the TEA promoter into the same genomic position as the V5 gene segment. Correct targeting was confirmed by Southern blotting. (J:149413)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
