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The transgenic construct has a 1.6 kb PCR fragment containing the Atoh1 enhancer in the 3' UTR of the Atoh1 gene, followed by the cre recombinase cDNA with a metallothionein I polyadenylation signal. The purified construct was injected into fertilized oocytes. Nine founder lines were established and crossed to the R26R reporter line. Three lines recapitulated the endogenous Atoh1 expression profile and two lines were characterized further. (J:149533)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
