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A 1.5 kb fragment encoding the Dll1 mesoderm-specific enhancer element (Dll1-msd) was cloned into a plasmid (pAKH) upstream of the beta-globin miminal promoter, and nuclear-localized cre recombinase (NLS-cre) and the beta-actin polyadenylation signal. The linearized purified fragment was microinjected into fertilized FVB/N eggs. Two founder lines were established with similar cre activity domains. Line 33 was chosen for further characterization. (J:148512)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
