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The coding sequence of Nog was cloned into a vector in front of an IRES-EGFP sequence under control of the chick beta-actin promoter and the CMV immediate-early enhancer. A STOP cassette flanked by loxP sites was inserted between the CAG promoter and the Noggin sequence. Excision of the STOP cassette by cre recombinase permits expression of Noggin. (J:149232)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
